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Tsc1 antibody

WebJul 25, 2005 · The polyclonal and monoclonal TSC1 antibodies were gifts of V. Ramesh (Massachusetts General Hospital, Boston, MA). Affinity-purified antibody against GST was prepared from anti-GST serum using GST immobilized on glutathione-Sepharose as an affinity matrix. The mouse monoclonal α-vinculin antibody was obtained from Upstate … WebFeb 25, 2024 · hamartin Antibody (C-8) is an IgG 2b κ mouse monoclonal hamartin antibody (also designated TSC1 antibody or TSC antibody) suitable for the detection of the hamartin protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. hamartin Antibody (C-8) is available as both the non-conjugated anti-hamartin antibody form, as well as …

TSC2 Gene - GeneCards TSC2 Protein TSC2 Antibody

WebMar 21, 2024 · In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, 28215400, 35772404).Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity … Weba 15 amino acid peptide from the middle region of human TSC1. TSC1 antibody will recognize both isoforms of TSC1. Packaging. 100 μg. Linkage. The action of this antibody can be blocked using blocking peptide SBP3505. Physical form. Solution in phosphate buffered saline containing 0.02% sodium azide. ionized plasma https://reneevaughn.com

TSC1 Polyclonal Antibody (PA5-20131) - Thermo Fisher Scientific

WebThis antibody binds to Yeast LCB2. Format: Liquid or Lyophilized: Storage: Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use: Purity > 90% was determined by SDS-PAGE: Purification: Purified with Protein A or G affinity chromatography: Cellular Localization: Endoplasmic reticulum; Other locations WebInvitrogen Anti-TSC1 Polyclonal, Catalog # PA5-20131. Tested in Western Blot (WB) and Immunocytochemistry (ICC/IF) applications. This antibody reacts with Human, Mouse, Rat … WebFeb 16, 2024 · This is a Validated Antibody Database (VAD) review about human TSC1, based on 29 published articles (read how Labome selects the articles), using TSC1 antibody in all methods.It is aimed to help Labome visitors find the most suited TSC1 antibody. Please note the number of articles fluctuates since newly identified citations are added … on the banks of the wabash

Anti-TSC-1 antibody (ab200728) Abcam

Category:TSC1 antibody (ABIN1955081) - antibodies-online.com

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Tsc1 antibody

TSC1 Antibody (600-401-FQ8) Rockland

WebRabbit TSC1 Rabbit pAb (A0720), validaed in WB,IHC,IF/ICC and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides free trial antibodies for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody. WebAug 24, 2012 · The endogenous interaction of TBC1D7 with the TSC1-TSC2 complex was confirmed in reciprocal immunoprecipitations with a panel of six unique antibodies to TSC1 or TSC2, along with an antibody raised against TBC1D7 (Figure 1 B), the specificity of which was confirmed through siRNA-mediated knockdown of TBC1D7 (Figure S1 E).TBC1D7 …

Tsc1 antibody

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WebAnti TSC1 pAb [Catalog No.: ATL-HPA074132] Toggle menu. Compare ; Phone: 760-431-4600 / Fax: 760-431-4604; Sign in or Register; Cart 0. Search. CURRENT PROMOTIONS. ... Primary Antibodies; Aicardi-Goutieres syndrome . All Aicardi-Goutieres syndrome; Labeled Proteins; Recombinant Antibodies; Alcohol Use Disorder . All Alcohol Use Disorder; WebThe regulation of the subcellular localization of phosphatase and tensin homologue (PTEN) is critical to its tumor-suppressing functions. Previously, we found that the activation of the phosphoinositide 3-kinase (PI3K)/Akt/mTOR/S6 protein kinase (S6K) cascade triggers the nuclear export of PTEN duri …

WebIgGy Antibody Selector – Quickly search hundreds of thousands of antibodies available for purchase from VWR by selecting common antibody features like antigen symbol and name, reactivity, clonality, conjugation, host, and other key factors. Antibodies used to identify and locate intracellular and extracellular proteins in common applications such as Western … WebNov 10, 2024 · Tsc1 was immunoprecipitated from HEK293 cell lysates using anti-Tsc1 antibody and immunoblotted with indicated antibodies to confirm chaperone, co-chaperone, and client protein interaction. IgG was used as control. FLAG-tagged Hsp90α N-, M-, and C-domains were transiently expressed and immunoprecipitated from HEK293 cells.

WebThis is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth. A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown. Application Note. Anti-TSC1 Antibody has been tested for use in ELISA and Western ... WebFeb 5, 2024 · How activated B cells build biosynthetic pathways and organelle structures necessary for subsequent robust antibody secretion is still unclear. The dominant model holds that nascent plasma cells adapt to increased antibody synthesis by activating the unfolded protein response (UPR) under the control of the transcription factor Xbp1.

WebImmunoprecipitation of TSC1 was performed on HAP1 cell lysates. Antibody-bead conjugates were prepared by adding 2 µg of TSC1 polyclonal antibody (Product # PA5 …

WebMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val640 of human TSC1. Background Tuberous … ionized pre water heater pipeWebMedium consistency between antibody staining and RNA expression data. Medium consistency between antibody staining and RNA expression data. WESTERN BLOT i Validation i. Uncertain i. Weak band of predicted size but with additional bands of higher intensity also present. ... TSC1-201. TSC1-203. TSC1-208. TSC1-212. TSC1-213. TSC1 … on the banks of the wabash far awayWebUrothelial carcinoma represents one of the most prevalent types of cancer worldwide, and its incidence is expected to grow. Although the treatment of the advanced disease was based on chemotherapy for decades, the developments of different therapies, such as immune checkpoint inhibitors, antibody drug conjugates and tyrosine kinase inhibitors, … ionized photoelectron spectroscopyWebRabbit anti Human TSC1 antibody recognizes an epitope within the internal region of the 130kDa tumour suppressor protein, Tumour sclerosis complex 1 (TSC1). Mutation within … on the banks of the riverWebNov 12, 2024 · TSC1/2-mutated PEComas sometimes respond to mTOR-inhibition therapy , but these drugs are mechanistically believed to be inefficient in TFE3-altered PEComa. MET-inhibitors, on the other hand, are active in alveolar soft part sarcoma with TFE3 rearrangement [ 20 ], a rare subtype of soft-tissue sarcoma, and could constitute a … on the banks rutgers blogWebPolyclonal Antibody for studying Hamartin/TSC1. Cited in 74 publications. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in-house, Hamartin/TSC1 Antibody (CST #4906) is ready to ship. ionized plasma reactorWebDr. Constantinos Demetriades is a Molecular Cell Biologist and a European Research Council (ERC) Grantee. Currently, he holds a Max Planck Research Group Leader position (Associate Professor level) at the Max Planck Institute for Biology of Ageing (MPI-AGE) in Cologne. His work focuses on the intricate molecular and cellular mechanisms of nutrient sensing and … ionized pool system