Phospho-erk5

Author: xgft

August undefined, 2024

WebAnti-phospho-ERK5 (pThr218/pTyr220) antibody produced in rabbit (Anti-BMK1); affinity isolated antibody, buffered aqueous glycerol solution; Each vial contains enough material … WebInvitrogen Anti-Phospho-ERK5 (Thr218, Tyr220) Polyclonal, Catalog # 44-612G. Tested in Western Blot (WB) and Immunocytochemistry (ICC/IF) …

Phospho-ERK5 (Thr219, Tyr221) Polyclonal Antibody

WebFeb 17, 2015 · ERK5 contains a kinase domain at the N-terminal, and the unique extended C-terminal includes multiple autophosphorylation sites that enhance ERK5-dependent transcription. However, the impact of phosphorylation at the various sites remain unclear. In this study, we examined the role of phosphorylation at the ERK5 C-terminal. WebPhospho-ERK5 (Thr218/Tyr220) Assay. Increased signal is observed with the titration of ERK5 positive cell lysate. Signal for negative lysate remains low throughout the titration. The p Phospho-ERK5 (Thr218/Tyr220) Assay provides a quantitative measure of the data obtained with the traditional Western blot. listrate iracing templets

The WNK1–ERK5 route plays a pathophysiological role in ovarian …

WebFeb 4, 2016 · The pre-B-cell receptor (pre-BCR) is an important checkpoint of B-cell development and is essential for a pre-B cell to traverse into an immature B cell. Here, we show that activation of myocyte enhancer factor 2 (Mef2) transcription factors (TFs) by the pre-BCR is necessary for initiating the subsequent genetic network. WebERK5 MAP kinase cascade has a crucial functions like- induction of special form of cardiac hypertrophy, enhanced neuronal survival and early steps of muscle cell differentiation. Anti-phospho-ERK5 (pThr 218 /pTyr 220) antibody can be used in immunostaining. Rabbit anti- phospho-ERK5 (pThr 218 /pTyr 220) antibody reacts specifically with ERK5 ... list recurring appointments in outlook 2016

Region-specific changes in the phosphorylation of ERK1/2 and ERK5 …

Alternative ERK5 regulation by phosphorylation during the …

WebERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. For Research Use Only. Not for use … WebMar 27, 2024 · Moreover, potential specific changes in the expression of Epac1/2 proteins may occur in subcellular cardiac compartments that would require more precise investigations. 47, 48 Indeed, Epac1 was shown previously to mediate the pro-hypertrophic effects of β-AR stimulation 49 through either its recruitment to β 1-ARs via β-arrestin2 47 … list referencyjny firmaWebMar 13, 2024 · Phospho-ERK5 TEY (3371) antibody was from Cell Signaling Technology 40,41. Phospho-T733 and phospho-S754 ERK5 antibodies were a kind gift from Dr. … impact bpo sdn bhd

"WebSep 29, 2009 · These are the extracellular regulated kinase (ERK)1/2 pathway, the ERK5 pathway, the p38 pathway and the c-Jun N-terminal kinase (JNK) pathway. In some forms of human breast cancer and in many experimental models of breast cancer progression, signalling through the ERK1/2 pathway, in particular, has been implicated as being … " - Phospho-erk5

Phospho-erk5

Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody

WebERK5 is a member of the mitogen-activated protein kinase (MAPK) family that, after stimulation, is activated selectively by dual phosphorylation in the TEY motif by MAPK … WebPhospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody detects endogenous levels of p44 and p42 MAP Kinase (Erk1 and Erk2) when phosphorylated either individually or dually at Thr202 and Tyr204 of Erk1 …

Did you know?

WebWestern blot - Anti-ERK5 (phospho T218 + Y220) antibody (ab5686) Peptide Competition: Extracts prepared from HEK293 cells transiently transfected with plasmids expressing … WebMar 10, 2024 · 研究证实，ox-ldl 与cd36 结合后可激活血小板内src、syk、plcγ2、pkc蛋白，使其发生磷酸化，进一步使nox2 激活。nox2 是血小板内介导ros 生成的关键蛋白，其活化可促进胞内产生大量的ros，进而使下游的erk5 发生磷酸化，促使血小板发生凋亡〔5，21〕 …

WebSep 1, 2009 · Representative western blots to show changes in phospho-ERK5 and total ERK5 are shown in Fig. 2A (upper panels) and quantification of these is shown in Fig. 2B. Total ERK5 protein levels doubled 24 hours after the initiation of differentiation (P<0.01) and then gradually decreased during the remainder of the period investigated. By contrast ... WebOct 11, 2024 · In addition, ERK5 activation was detected by a band shift which is a characteristic of phosphorylated ERK5. However, flow-induced Akt phosphorylation was not affected by PAR-1 knockdown using PAR ...

WebERK5 Antibodies. Antibodies that detect ERK5 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Flow Cytometry, Immunohistochemistry and Immunoprecipitation. These antibodies target ERK5 in Human, Mouse, Rat and Non-human primate samples. Our ERK5 monoclonal, polyclonal and recombinant monoclonal ... WebERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization. References (0)

WebJun 23, 2024 · Except for ERK5, which contains a long carboxy (C)-terminal domain, the conventional MAPKs consist of a single kinase domain (KD) with short amino (N) and C terminals. ... their phospho-activating ...

WebAnti-phospho-ERK5 (pThr218/pTyr220) antibody can be used in immunostaining. Rabbit anti- phospho-ERK5 (pThr218/pTyr220) antibody reacts specifically with ERK5 (88 kD) of … impact box bladeWebThe result that phospho-ERK5 was exclusively increased in DRG neurons, while phospho-ERK1/2 was increased in the spinal cord and the urinary bladder after cystitis, suggests a region-specific effect of neurotrophins on micturition pathways following bladder inflammation. Publication types Comparative Study Research Support, Non-U.S. Gov't impact bowl mopWebAug 29, 2008 · The role of the MAP kinase, extracellular signal-regulated kinase 5 (ERK5) remains unknown, however it is involved in cell differentiation and survival as highlighted by the embryonic lethality of the ERK5 knockout. ERK5 can be activated by growth factors and other extracellular signals. impact bpoWebMSD phosphoprotein assays provide a rapid and convenient methodfor measuring the levels of protein targets within a single, small-volume sample. The assays are available in both singleplex and multi plex formats. In a singleplex assay, an antibody for a specific protein target is coated on one electrode (or “spot”) per well. impact bpo services pte ltdWebInvitrogen Anti-Phospho-ERK5 (Thr219, Tyr221) Polyclonal, Catalog # PA5-114573. Tested in Western Blot (WB) and Immunohistochemistry (PFA fixed) (IHC (PFA)) applications. … impact bpmWebPhospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody detects endogenous levels of p44 and p42 MAP Kinase (Erk1 and Erk2) when phosphorylated either individually or dually at Thr202 and Tyr204 of Erk1 … impact boxesWebDec 17, 2013 · ERK5 phosphorylation was assessed in the immunoprecipitate using a phosphospecific antibody. Data (mean +/- SEM of 3 independent experiments) were normalised using HA-ERK5 as loading control and expressed as fold-induction over basal conditions (*p<0.05, two-tailed T-test). impact bpco bronche