Web2 days ago · Bei Zugabe des NAE1-Inhibitors MLN4924 beobachteten die Bonner Forschenden daher in Cisplatin-resistenten Hodenkrebs-Zellen eine Re-Sensibilisierung gegenüber dem Zytostatikum. Dass Bindegewebszellen durch die Behandlung nicht beeinträchtigt wurden, lässt hoffen, dass es bei Anwendung nur schwache … WebApr 5, 2024 · characteristics of cisplatin-induced nephrotoxicity, focusing on its pharmacokinetic profile and renal toxicities, in order to facilitate the use of effective pre-ventive strategies. A literature search of PubMed (MEDLINE) was performed to identify articles published between 1980 and 2024 using the search keyword “Cisplatin AND …
PHYSICAL COMPATIBILITY AND CHEMICAL STABILITY OF CISPLATIN …
WebAug 2, 2016 · Mannitol is an osmotic diuretic that increases urine output. It may be used before cisplatin to reduce the nephrotoxic effects of cisplatin. Not all institutions use … WebFor cisplatin, hydration is always indicated and mannitol may be useful in selected settings. Furosemide is probably not generally useful. For carboplatin, hydration is important for patients with impaired renal function and for patients receiving high doses of … crew chief program
The Role of Mannitol as a Nephroprotectant in Patients Receiving ...
WebMannitol combined with hydration significantly prevented cisplatin-induced nephrotoxicity. Therefore, mannitol should be considered among patients with cancer, treated with … WebJun 23, 2024 · The administration of mannitol or a diuretic is also required when the administrated cisplatin dose is higher than 60 mg/m 2 of body surface. It is necessary that the patient drinks large quantities of liquids for 24 hours after the cisplatin infusion to ensure adequate urine secretion. 4.3 Contraindications buddhist auspicious symbols