Hif1a genecard
http://html.rhhz.net/SWJSTB/html/2016-8-8.htm Web1 de jun. de 2024 · The TiPARP nuclear bodies recruit both HIF-1α and an E3 ubiquitin ligase HUWE1, which promotes the ubiquitination and degradation of HIF-1α. Similarly, TiPARP promotes the degradation of c-Myc and estrogen receptor. By suppressing HIF-1α and other oncogenic transcription factors, TiPARP exerts strong antitumor effects both in …
Hif1a genecard
Did you know?
Web25 de jun. de 2015 · Xihua Chen, Jianbing Liu, Bin He, Yunfeng Li, Shuyan Liu, Bin Wu, Shufang Wang, Shucheng Zhang, Xiangbo Xu, Jiedong Wang, Vascular endothelial growth factor (VEGF) regulation by hypoxia inducible factor-1 alpha (HIF1A) starts and peaks during endometrial breakdown, not repair, in a mouse menstrual-like model, Human … Web24 de mai. de 2024 · 1.2 疾病相关靶点检索 以“prostatitis”为关键 词,分 别 在GeneCard ... 靶点PPI分析,生物功能分析和通路富集结果显示AKT1、STAT3、ESR1、TNF、MDM2、PTGS2、PGR、NFKB1、HIF1A、MAPK14、PIK3CA、IL1B等是关键靶点;蛋白激酶活性、一氧化氮生物合成过程的正调控、RNA ...
Web10 de abr. de 2024 · Summary. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a … WebHypoxia-inducible factor-1 (HIF-1) has been recognized as an important cancer drug target. Many recent studies have provided convincing evidences of strong correlation between …
WebGene target information for HIF1A - hypoxia inducible factor 1 subunit alpha (human). Find diseases associated with this biological target and compounds tested against it in … Web21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, … TRMT5 (TRNA Methyltransferase 5) is a Protein Coding gene. Diseases … Complete information for HIF1A-AS3 gene (RNA Gene), HIF1A Antisense RNA 3, … Complete information for HIF1A-AS1 gene (RNA Gene), HIF1A Antisense RNA 1, … Complete information for SRMP2 gene (Pseudogene), SRM Pseudogene 2, …
WebHIF-1 alpha and HIF-1 beta (ARNT) mRNAs were detected in all human, mouse, and rat organs assayed and mRNA expression was modestly induced in rodents subjected to …
WebHypoxia-inducible protein 2 (HIG2) has been implicated in canonical Wnt signaling, both as target and activator. The potential link between hypoxia and an oncogenic signaling pathway might play a pivotal role in renal clear-cell carcinoma characterized by constitutive activation of hypoxia-inducible factors (HIFs), and hence prompted us to analyze HIG2 regulation … plug in led shop lights 34Web21 de mar. de 2024 · Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including … princeton towers apartments birmingham alWeb2 de out. de 2009 · The hypoxia-induced phenotypic changes in tumors result, at least partially, from the induction of hypoxia-responsive genes, such as chemokine receptor … princeton tours of campus