Csn6-wt
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Csn6-wt
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WebNov 28, 2013 · CSN6 is one subunit of the constitutive photomorphogenesis 9 (COP9) signalosome (CSN), which is an evolutionarily conserved multiprotein complex found in plants and animals and originally described as a repressor of light-dependent growth and transcription in Arabidopsis. CSN is homologous to the 19S lid subcomplex of the 26S …
WebCSN6 CSN8 WT ΔCSNAP 55 55 55 45 35 45 25 Cul1 Cul2 Cul3 Cul4AB Cul5 WT ΔCSNAP 75 75 75 75 100 D Binding (KD, nM) CSN: ΔCSNAP WT ΔCSNAP CSN5H138A WT CSN5H138A Substrate Cul1/Rbx1: 310 >1000 8 ... WebFeb 23, 2024 · CSN6, a critical subunit of the constitutive photomorphogenesis 9 (COP9) signalosome (CSN), has received attention as a regulator of the degradation of cancer-related proteins such as p53, c-myc and c-Jun, through the ubiquitin-proteasome system, suggesting its importance in cancerogenesis. However, …
WebCSN6 enhances neddylation of Cullin-1 via its MPN domain (a) Neddylation status of Cullin in gel filtration chromatography fractions from spleen extracts from Csn6 +/+ (wt) and … WebNov 14, 2014 · Both wt CSN6 and myc-tagged 6N5C increased Cullin-1 neddylation, while both wt CSN5 and myc-tagged 5N6C reduced Cullin-1 neddylation (Fig. 4g), suggesting that the MPN domain of CSN6 functions differently from that of CSN5 and is the critical region for facilitation of Cullin-1 neddylation.
WebCSN6 Promotes the Migration and Invasion of Cervical Cancer Cells by Inhibiting Autophagic Degradation of Cathepsin L ... Mao Z, Sang MM, Chen C, Zhu WT, Gong YS, Pei D. CSN6 Promotes the Migration and Invasion of Cervical Cancer Cells by Inhibiting Autophagic Degradation of Cathepsin L. Int J Biol Sci 2024; 15(6):1310-1324. …
WebMay 3, 2016 · Then to address the biological significance of IDEF1 accumulation in CSN6 antisense lines, we measured IDEF1 target gene … buy blue spotWebAug 22, 2016 · CSN6, a critical subunit of the constitutive photomorphogenesis 9 (COP9) signalosome (CSN), has received attention as a regulator of the degradation of cancer-related proteins such as p53, c-myc ... celery t shirtWebNov 14, 2014 · MEF cells were prepared from 13.5-day embryos derived from wild-type (wt) Csn6 þ / þ and Csn6 þ / mice. After 4 days of culture, cell lysates were After 4 days of … buy blue spruceWebMar 30, 2024 · Importantly, CSN6 reduced the steady-state expression of TRIM21-WT but not a TRIM21 (C16A, C31A and H33W) RING-finger ((ligase-dead (LD)) mutant in a … celery trong djangoWebAug 10, 2015 · The CSN6 S148A mutant did not respond to EGF-induced upregulation, whereas the WT CSN6 was upregulated by EGF. Even in the absence of EGF, the … celery traductionhttp://www.segmentedturning.com/links/georgia-wt.html celery transportWebNeural precursor cell expressed, developmentally downregulated 9 (NEDD9), is a focal adhesion scaffold protein which has been associated with metastas… buy blue spruce trees near me