WebKidney injury molecule-1 (KIM-1) is a novel biomarker promising the diagnosis of AKI in early stages. We studied whether urinary and serum KIM-1 (KIM-1 U and KIM-1 S ) concentrations were useful in predicting cisplatin-induced AKI in early stages. Methods: We prospectively analysed 22 patients on cisplatin treatment. WebFor some tumors, cisplatin appears to be superior to carboplatin in terms of therapeutic effectiveness (germ cell tumors, bladder cancer, head and neck cancer), while for others, effectiveness is comparable (lung cancer, ovarian cancer). Toxicity profiles are distinctly different for the two analogu …
Cisplatin overdose: toxicities and management - PubMed
WebFeb 5, 2024 · Cisplatin and Oxaliplatin: Our Current Understanding of Their Actions. … WebCisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can cause acute kidney injury and chronic kidney disease. Preclinical studies have provided insights into the cellular … how to share a screencastify video
Cisplatin in cancer therapy: molecular mechanisms of action
Web1. INTRODUCTION. Lung cancer has a high worldwide prevalence and is usually malignant, with the highest cancer‐related mortality. 1 , 2 Lung cancers can be grossly classified into non‐small cell lung carcinoma (NSCLC), accounting for about 85% of lung cancers, and small cell lung carcinoma, which is less prevalent. NSCLC can be further divided into … WebGemcitabine and cisplatin chemotherapy is an active combination in the treatment of platinum-resistant ovarian and peritoneal carcinoma Invest New Drugs. 2004 Nov;22 (4):475-80. doi: 10.1023/B:DRUG.0000036690.14585.a3. Authors Devansu Tewari 1 , Bradley J Monk , Mark Hunter , Camille A Falkner , Robert A Burger Affiliation WebOct 5, 2014 · Cisplatin derivatives are used as the mainline treatment of ovarian cancer, … how to share a screen recording